Topoisomerase II checkpoints: Universal mechanisms that regulate mitosis
- Duncan J. Clarke(corresponding author),
- Amit C. Vas,
- Catherine A. Andrews,
- ,
- Juan F. Giménez-Abián
- University of Minnesota Medical School,
- Department of Genetics; Cell Biology and Development,
- CSIC - Centro de Investigaciones Biológicas Margarita Salas (CIB)
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Abstract
Checkpoint controls confer order to the cell cycle and help prevent genome instability. Here we discuss the Topoisomerase II (Decatenation) Checkpoint which functions to regulate mitotic progression so that chromosomes can be efficiently condensed in prophase and can be segregated with high fidelity in anaphase.
Bibliographic Information
Output type
Research Output:
Contribution to journal
Short survey
Peer-reviewOriginal language
EnglishPages from-to (Number of pages)
Pages 1925-1928 (4 pages)Journal (Volume, Issue Number)
Cell Cycle (Volume 5, Issue 17)Publication milestones
- Published - 01/09/2006
Publication status
Published - 01/09/2006
ISSN
1538-4101Publication IDs
- Scopus: 33748950990
- PubMed: 16940751