Direct synthesis of trimethyl(2-phenoxyethyl)silanes from aromatic fluorides
- Scott A. Grecianb, d(Author),
- Sabine Hadidab, c(Author),
- ,
- bDuPont,
- cVertex Pharmaceuticals Inc.,
- dUniversity of Kansas
Research Output: Contribution to journal Article Peer-review
Abstract
A direct synthesis of trimethyl(2-phenoxyethyl)silanes from the corresponding aromatic fluorides and 2-(trimethylsilyl)ethanol was developed. A variety of substituents were tolerated and a substitution reaction using 1-bromo-3-chloro-5-fluorobenzene was demonstrated.
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